2014 International Conference on Systems Biology (ISB)

Qingdao, China, October 24-27, 2014
Edited by: Luonan Chen, Xiang-Sun Zhang, Ling-Yun Wu, and Yong Wang

Copyright ©2014 by the Institute of Electrical and Electronics Engineers, Inc. All rights reserved.

Copyright and Reprint Permission
Abstracting is permitted with credit to the source. Libraries are permitted to photocopy beyond the limit of U.S. copyright law for private use of patrons those articles in this volume that carry a code at the bottom of the first page, provided the per-copy fee indicated in the code is paid through Copyright Clearance Center, 222 Rosewood Drive, Danvers, MA 01923. For other copying, reprint or republication permission, write to IEEE Copyrights Manager, IEEE Operations Center, 445 Hoes Lane, Piscataway, NJ 08854. All rights reserved. Copyright ©2014 by IEEE.

IEEE Catalog Number CFP14ISB-USB
ISBN 978-1-4799-7293-7



Topological Characterization of Housekeeping Genes in Human Protein-Protein Interaction Network
Pei Wang, Yuhuan Zhang, Jinhu Lu, Xinghuo Yu

A dynamic programming algorithm for nucleosome positions alignment
Yiru Zhang, Changchang Cao, Hongde Liu, Xiao Sun

A Class-Information-based SNMF Method for Selecting Characteristic Genes
Jin-Xing Liu, Chun-Xia Ma, Ying-Lian Gao, Jian Liu, Chun-Hou Zheng

Global analysis of a delay virus dynamics model with Beddington-DeAngelis incidence rate and CTL immune response
Lisha Liang, Yongmei Su

Dynamical behaviour of a delay differential equation of Hepatitis B Virus
Dayun Wu, Yongmei Su

Prediction of hepatotoxicity of traditional Chinese medicine compounds by support vector machine approach
Ludi Jiang, Yusu He, Yanling Zhang

Antitumor mechanism research of cryptotanshinone by module-based network analysis
Shichao Zheng, Zhenzhen Ren, Shifeng Wang, Yanling Zhang, Yanjiang Qiao

Discovery of natural products for dual pharmacology CETP inhibitors and niacin receptor agonists
QIAO Lian-sheng, CAI Yi-lian, HE Yu-su, YANG Yong-qiang, JIANG Lu-di, ZHANG Yan-ling

A combination of pharmacophore modeling, molecular docking and virtual screening for NPC1L1 receptor inhibitors from Chinese herbs
Xiaoqian Huo, Ludi Jiang, Xi Chen, Yusu He, Yongqiang Yang, Yanling Zhang

In silico analysis of mutations in PITX3 gene
Abida Arshad, Rashda Abbasi, Christian MK Sieber, Muhammad Arshad, Nafees Ahmad

A Tensor-Based Markov Chain Method for Module Identification from Multiple Networks
Chenyang Shen, Shuqin Zhang, Michael K. Ng

Comparison of Multi-Sample Variant Calling Methods for Whole Genome Sequencing
Kwangsik Nho, John D. West, Huian Li, Robert Henschel, Apoorva Bharthur, Michel C. Tavares, Michael W. Weiner, Robert C. Green, Arthur W. Toga, Andrew J. Saykin

Testing Multiple Hypotheses through IMP Weighted FDR Based on a Genetic Functional Network with Application to a New Zebrafish Transcriptome Study
Jiang Gui, Walter Taylor, Jason H. Moore, Con Sullivan, Carol H. Kim, Casey S. Greene

Comparative analysis of RNA-seq data from polyA RNAs selection and ribosomal RNAs deletion protocol by strand-specific RNA sequencing technology
Lingjie Fu, Meili Chen, Jiayan Wu, Jingfa Xiao, Zhewen Zhang

Systematic Identification of Local Structure Binding Motifs in Protein-RNA Recognition
Zhi-Ping Liu

Evolution Analysis for HA Gene of Human Influenza A H3N2 Virus (1990 - 2013)
Su-Li Li, Meng-Zhe Jin, Zhao-Hui Qi

A Semi-tensor Product Approach for Probabilistic Boolean Networks
Xiaoqing Cheng, Yusan Qiu, Wenpin Hou, Wai-Ki Ching

Cross-Platform and Cross-Device Pedometer System Designed for Healthcare Services
Yongjin Kwon , Kyuchang Kang, Changseok Bae, Rebekah Jiyoung Cha

A Gene Link-based Method for Identifying Differential Gene Pathways
Zirui Zhang, Ke Chen, Hong-Qiang Wang

Reversal DNA methylation patterns for cancer diagnosis
Hongdong Li , Guini Hong, Zheng Guo

Functional analysis of differential mRNAs in cancer peripheral blood: reflection of population shifts in myeloid-origin and lymphoid-origin cells
Guini Hong, Hongdong Li, Wenjing Zhang, Zheng Guo, Beibei Chen, Hui Xu, Lu Ao

VaccineWatch: a monitoring system of vaccine messages from social media data
Somrak Numnark, Supawadee Ingsriswang, Duangdao Wichadakul

A New Approach for Estimating the Progression of Pancreatic Cancer
Shuhao Sun, Fima Klebaner, Tianhai Tian

Dissecting the Obesity Disease Landscape: Identifying Gene-Gene Interactions that are Highly Associated with Body Mass Index
Rishika De, Shefali S. Verma, IBC BMI Working Group, Michael V. Holmes, Folkert W. Asselbergs, Jason H. Moore, Brendan J. Keating, Marylyn D. Ritchie, Diane Gilbert-Diamond

Network-based detection of Disease Modules and Potential Drug Targets in Intractable Epilepsy
Hongwei Chu, Xuezhong Zhou, Guangming Liu, Minghui Lv, Xiaofeng Zhou, Yiwei Wang, Lin Liu, Xing Li, Pin Sun, Yizhun Zhu, Changkai Sun

Mining Correlation Patterns of Taxa, Pathways and Environmental Factors with An Improved Weighted Network Community Detection Algorithm
Xiao-Ying Yan, Shao-Wu Zhang, Ze-Gang Wei, Wei-Feng Guo

cLP: Linear Programming with Biological Constraints and its Application in Classification Problems
Manli Zhou, Youxi Luo, Guoqin Mai, Fengfeng Zhou

Detection of SNP-SNP Interaction based on the Generalized Particle Swarm Optimization Algorithm
Changyi Ma, Junliang Shang, Shengjun Li, Yan Sun

An Entropy-based Statistical Workflow Provides Noise-Minimizing Biological Annotation for Muscular Aging
Theodoros Koutsandreas, Ioannis Valavanis, Eleftherios Pilalis, Aristotelis Chatziioannou

Measuring the Similarity of Protein Structures Using Image Local Feature Descriptors SIFT and SURF
Morihiro Hayashida, Hitoshi Koyano, Tatsuya Akutsu

Incorporating feature reliability in false discovery rateestimation improves statistical power to detect differentially expressed features
Elizabeth Chong, Yijian Huang, Hao Wu, Tianwei Yu, Nima Ghasemzadeh, Karan Uppal, Arshed A. Quyyumi, Dean P. Jones

PRECISE: PRivacy-prEserving Cloud-assisted quality Improvement Service in healthcare
Feng Chen, Shuang Wang, Noman Mohammed, Samuel Cheng, Xiaoqian Jiang

The Correlation and Regression Analysis on Aerosol Optical Depth, Ice Cover and Cloud Cover in Greenland Sea
Bo Qu, Albert J. Gabric, Peijuan Gu, Meifang Zeng

Neural fate decisions mediated by oscillatory and sustained Hes1
Shanshan Li, Zengrong Liu, Ruiqi Wang

An epigenetic switch involving a positive feedbacK loop linking inflammation to cancer effected by Myc and miRNA-17-92 microRNA cluster
Jichun Chang, Ruiqi Wang

Network-based Analysis of Time Series RNA-Seq Gene Expression Data by Integrating the Interactome and Gene Ontology Information
Yuji Zhang

Evidence based computational drug repositioning candidate screening pipeline design: Case Study
Qian Zhu, Hongfang Liu, Yuji Zhang, Jiabei Wang

Evidence Based Disease Network Construction towards Drug Repositioning
Liwei Wang, Jiabei Wang, Qian Zhu

Predicting Golgi-resident proteins in plants by incorporating N-terminal transmembrane domain information in the general form of Chou's pseudo-amino acid compositions
Yasen Jiao, Pufeng Du, Xiaoquan Su

Bi-objective Optimization of a Continuous Biological Process
Gongxian Xu, Ying Liu, Chao Yu, Dan Su

Author Index